# Vaccine Development and Immunology Status: public Confidence: medium (0.82) (verified) Last verified: 2026-05-28 Generation: ai_structured ## TL;DR Vaccine development spans early smallpox vaccination, modern mRNA vaccine platforms, and population-level survival gains from immunization. ## Core Explanation This repair replaces unmapped claims with source-aligned facts from WHO, Nature Reviews Drug Discovery, and The Lancet. ## Further Reading - [WHO: History of smallpox vaccination](https://www.who.int/news-room/spotlight/history-of-vaccination/history-of-smallpox-vaccination) - [mRNA vaccines for infectious diseases](https://www.nature.com/articles/s41573-021-00283-5) - [The contribution of vaccination to improved survival and health](https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(24)00850-X/fulltext)