{
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  "@type": "article",
  "@id": "https://anchorfact.org/kb/protein-structure-prediction",
  "headline": "Protein Structure Prediction: AlphaFold, RoseTTAFold, and AI-Driven Structural Biology",
  "description": "Protein structure prediction has been transformed by AI — from AlphaFold2's historic 2020 breakthrough predicting static 3D structures to current frontiers: simulating protein dynamics, predicting multi-protein complexes, and designing entirely new proteins with specified functions. The 2024 Nobel Prize in Chemistry recognized this revolution, but fundamental challenges remain.",
  "dateCreated": "2026-05-24T02:49:13.652Z",
  "dateModified": "2026-05-24",
  "author": {
    "@type": "Organization",
    "name": "AnchorFact"
  },
  "publisher": {
    "@type": "Organization",
    "name": "AnchorFact",
    "url": "https://anchorfact.org"
  },
  "license": "https://creativecommons.org/licenses/by/4.0/",
  "anchorfact:confidence": "high",
  "anchorfact:generationMethod": "ai_assisted",
  "citation": [
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      "@type": "CreativeWork",
      "name": "The latest AI breakthroughs in structural biology: protein conformational landscapes and de novo design",
      "sameAs": "https://www.nature.com/articles/s42003-026-10112-3"
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    {
      "@type": "CreativeWork",
      "name": "Artificial intelligence methods for protein folding and design",
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